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Article

Association of the PIM3 allele of the alpha-1-antitrypsin gene with chronic obstructive pulmonary disease.

Clinical biochemistry - 1 May 2005

Gupta J, Bhadoria D P, Lal M K, Kukreti R, Chattopadhaya D, Gupta V K, Dabur R, Yadav V, Chhillar A K, Sharma G L

Abstract excerpt

OBJECTIVE: The study investigated the association of genetic polymorphism of the alpha1AT gene with COPD. DESIGN AND METHODS: The mutations and polymorphism of alpha1AT gene were investigated by DNA sequence analysis using polymerase chain reaction. RESULTS: The frequency of the PIM3 allele in COPD patients was found to be significantly higher than the controls (P < 0.0001). Five SNPs, including a novel SNP...

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Topics

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Share to alpha 1-Antitrypsin
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymerase Chain Reaction

Share to Polymorphism, Single Nucleotide

Share to Pulmonary Disease, Chronic Obstructive

Share to Sequence Analysis, DNA

Share to Smoking

Source

Identifiers

PMID: 15820782
DOI: 10.1016/j.clinbiochem.2005.01.016

Genes

PIM3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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