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Article

Identification of spliced variants of the proto-oncogene HDM2 in colorectal cancer.

Cancer - 15 Feb 2012

Yu Zhiwei, Zhang Bin, Cui Binbin, Wang Yihui, Han Peng, Wang Xishan

Abstract excerpt

BACKGROUND: The human double minute 2 (hdm2) oncogene is a negative regulator of the p53 gene. Expression and alternative splicing of the hdm2 gene may contribute to colorectal cancer development or progression. This study aimed to determine the presence and identification of aberrant mRNA transcripts of hdm2 in colorectal cancer tissues and cell lines, and determine the nature of their association with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21761395
DOI: 10.1002/cncr.26330

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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