Article
Evolution of histone H3: emergence of variants and conservation of post-translational modification sites.
Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Feb 2012
Waterborg Jakob H
Abstract excerpt
Histone H3 proteins are highly conserved across all eukaryotes and are dynamically modified by many post-translational modifications (PTMs). Here we describe a method that defines the evolution of the family of histone H3 proteins, including the emergence of functionally distinct variants. It combines information from histone H3 protein sequences in eukaryotic species with the evolution of these species as...
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