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Article

Establishment of Human Trophoblast Progenitor Cell Lines from the Chorion

13 Jul 2011

Abstract excerpt

Placental trophoblasts are key determinants of in utero development. Mouse trophoblast (TB) stem cells, which were first derived over a decade ago, are a powerful cell culture model for studying their self-renewal or differentiation. Our attempts to isolate an equivalent population from the trophectoderm of human blastocysts generated colonies that quickly differentiated in vitro. This finding suggested that the...

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PMID: 21755573
DOI: 10.1002/stem.686

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