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Integrin α4-positive human trophoblast progenitors: functional characterization and transcriptional regulation

15 Apr 2016

Abstract excerpt

STUDY QUESTION: What are the functional characteristics and transcriptional regulators of human trophoblast progenitor cells (TBPCs)? SUMMARY ANSWER: TBPC lines established from the human smooth chorion by cell sorting for integrin α4 expressed markers of stemness and trophoblast (TB) stage-specific antigens, invaded Matrigel substrates and contributed to the cytotrophoblasts (CTBs) layer of smooth chorion...

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PMID: 27083540
DOI: 10.1093/humrep/dew077

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