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Article

Reappearance of minority K103N HIV-1 variants after interruption of ART initiated during primary HIV-1 infection.

PloS one - 1 Jan 2011

Metzner Karin J, Leemann Christine, Di Giallonardo Francesca, Grube Christina, Scherrer Alexandra U, Braun Dominique, Kuster Herbert, Weber Rainer, Guenthard Huldrych F

Abstract excerpt

BACKGROUND: In the Zurich Primary HIV infection study (ZPHI), minority drug-resistant HIV-1 variants were detected in some acutely HIV-1-infected patients prior to initiation of early antiretroviral therapy (ART). Here, we investigated the reappearance of minority K103N and M184V HIV-1 variants in these patients who interrupted efficient early ART after 8-27 months according to the study protocol. These mutations...

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Identifiers

PMID: 21754996
DOI: 10.1371/journal.pone.0021734
PMCID: PMC3130779

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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