Article
Trajectories of brain and hippocampal atrophy in FTD with mutations in MAPT or GRN.
Neurology - 26 Jul 2011
Whitwell J L, Weigand S D, Gunter J L, Boeve B F, Rademakers R, Baker M, Knopman D S, Wszolek Z K, Petersen R C, Jack C R, Josephs K A
Abstract excerpt
OBJECTIVE: To use multiple serial MRI to assess rates and trajectories of brain and hippocampal atrophy in subjects with frontotemporal dementia (FTD) with progranulin (GRN) or microtubule-associated protein tau (MAPT) gene mutations. METHODS: In this case-control study, we identified 8 subjects with mutations in GRN and 12 subjects with mutations in MAPT who had at least 2 serial MRIs. Serial MRIs were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.