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Article

Genome-wide DNA profiling better defines the prognosis of chronic lymphocytic leukaemia.

British journal of haematology - 1 Sept 2011

Rinaldi Andrea, Mian Michael, Kwee Ivo, Rossi Davide, Deambrogi Clara, Mensah Afua A, Forconi Francesco, Spina Valeria, Cencini Emanuele, Drandi Daniela, Ladetto Marco, Santachiara Rita, Marasca Roberto, Gattei Valter, Cavalli Franco, Zucca Emanuele, Gaidano Gianluca, Bertoni Francesco

Abstract excerpt

The integration of molecular and clinical information to tailor treatments remains an important research challenge in chronic lymphocytic leukaemia (CLL). This study aimed to identify genomic lesions associated with a poor outcome and a higher risk of histological transformation. A mono-institutional cohort of 147 cases was used as the test series, and a multi-institutional cohort of 176 cases as a validation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukemia, Lymphocytic, Chronic, B-Cell

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Identifiers

PMID: 21749360
DOI: 10.1111/j.1365-2141.2011.08789.x

Genes

MYC
MYCN
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