Article
Discovery of a novel tumour metastasis-promoting gene, NVM-1.
The Journal of pathology - 1 Sept 2011
Thiele Wilko, Novac Natalia, Mink Sigrun, Schreiber Caroline, Plaumann Diana, Fritzmann Johannes, Cremers Natascha, Rothley Melanie, Schwager Christian, Regiert Thomas, Huber Peter E, Stein Ulrike, Schlag Peter, Moll Jürgen, Abdollahi Amir, Sleeman Jonathan P
Abstract excerpt
We have previously reported that over-expression of a panel of 119 genes correlates with the metastatic potential of pancreatic carcinoma cells. We sought to identify and functionally characterize candidate tumour metastasis promoting genes among this library using a secondary phenotype-assisted screen. Here we report the discovery of the metastasis-promoting function of a hitherto not characterized gene located...
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