Article
LIV-1 enhances the aggressive phenotype through the induction of epithelial to mesenchymal transition in human pancreatic carcinoma cells.
International journal of oncology - 1 Oct 2009
Unno Jun, Satoh Kennichi, Hirota Morihisa, Kanno Atsushi, Hamada Shin, Ito Hiromichi, Masamune Atsushi, Tsukamoto Nobukazu, Motoi Fuyuhiko, Egawa Shinichi, Unno Michiaki, Horii Akira, Shimosegawa Tooru
Abstract excerpt
LIV-1 is a downstream target of STAT3 and is essential for the nuclear localization of Snail, a master regulator of epithelial to mesenchymal transition (EMT). Little is known about the association of LIV-1 with pancreatic carcinoma development, therefore, expression of LIV-1 mRNA was analyzed by...
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