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Article

Molecular Signature of MT1-MMP: Transactivation of the Downstream Universal Gene Network in Cancer

1 Jun 2008

Abstract excerpt

Invasion-promoting MT1-MMP is directly linked to tumorigenesis and metastasis. Our studies led us to identify those genes, the expression of which is universally linked to MT1-MMP in multiple tumor types. Genome-wide expression profiling of MT1-MMP-overexpressing versus MT1-MMP-silenced cancer cells and a further data mining analysis of the preexisting expression database of 190 human tumors of 14 cancer types...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 18519667
DOI: 10.1158/0008-5472.can-07-6458

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