Article
Gene expression patterns associated with the metastatic phenotype in rodent and human tumors.
Cancer research - 15 Feb 2001
Nestl A, Von Stein O D, Zatloukal K, Thies W G, Herrlich P, Hofmann M, Sleeman J P
Abstract excerpt
Using subtractive technology, we have generated metastasis-associated gene expression profiles for rat mammary and pancreatic adenocarcinomas. Several genes whose expression is thought to be related to tumor progression such as c-Met, urokinase-type plasminogen activator receptor, ezrin, HMG-1, oncomodulin, cathepsin, and caveolin were thereby isolated. Half of the metastasis-associated clones showed no...
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