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Article

Poly(I:C) induce bone marrow precursor cells into myeloid-derived suppressor cells.

Molecular and cellular biochemistry - 1 Dec 2011

Liu Cong, Zhang Chaoxiong, Lu Hongjuan, Cai Jianming, Wang Zhigang, Chen Jie, Liu Fang, Wu Zhumei, Liu Xiaogang, Sun Weimin

Abstract excerpt

Dendritic cells (DC) and myeloid-derived suppressor cells (MDSC) are important cells involved in immune response. DC can be generated from mouse bone marrow (BM) in the presence of granulocyte-macrophage colony-stimulating factor (GM-CSF) and IL-4. Recent studies have revealed that combined treatment of bone marrow MDSC with LPS plus IFN-γ inhibited the DC development but enhanced MDSC functions, such as NO...

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PMID: 21744070
DOI: 10.1007/s11010-011-0982-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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