Article
CpG oligodeoxynucleotide induces bone marrow precursor cells into myeloid-derived suppressor cells.
Molecular medicine reports - 1 Oct 2013
Chen Jie, Deng Chengyu, Shi Qingmin, Jiang Jun, Zhang Yongbo, Shan Wei, Sun Weimin
Abstract excerpt
Dendritic cells (DCs) and myeloid-derived suppressor cells (MDSCs) perform a number of functions in different immunological settings. In standard in vitro experiments, DCs are produced from mouse bone marrow (BM) cells in the presence of granulocyte-macrophage colony-stimulating factor (GM-CSF) and IL-4. Our previous study demonstrated that BM precursor cells could differentiate into MDSCs when co-cultured with...
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