Article
No evidence for a correlation of glutathione S-tranferase polymorphisms and chronic rhinosinusitis.
Rhinology - 1 Jun 2011
Fruth K, Best N, Amro M, Ingel K, Gosepath J, Mann W J, Brieger J
Abstract excerpt
OBJECTIVE: Cellular detoxification mechanisms are mandatory for cellular protection against oxidative stress and reactive oxygen species. One major group of antioxidative active enzymes involved in cellular detoxification are the Glutathione S-Transferases (GST). Multiple subtypes like GSTM1, GSTP1, and GSTT1 and variants of them are known, arising from allelic variations of the GST loci. Moreover, functional...
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