Article
Identification and characterization of common B cell epitope in bovine leukemia virus via high-throughput peptide screening system in infected cattle.
Retrovirology - 30 Dec 2015
Bai Lanlan, Otsuki Hiroyuki, Sato Hirotaka, Kohara Junko, Isogai Emiko, Takeshima Shin-nosuke, Aida Yoko
Abstract excerpt
BACKGROUND: Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leukosis, the most common neoplastic disease of cattle. BLV is closely related to human T cell leukemia virus. B cell epitopes are important for the use of antibodies as therapeutic agents, the epitope-driven vaccine design, and immunological assays. A common B cell epitope for BLV has not yet been found due to individual...
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