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Article

Kallikrein-related peptidase genes as promising biomarkers for prognosis and monitoring of human malignancies

20 Mar 2010

Abstract excerpt

Tissue kallikrein (KLK1) and the kallikrein-related peptidase (KLK2-15) genes encode for a subgroup of 15 homologous secreted serine proteases possessing numerous physiological roles, such as the regulation of blood pressure, hormone processing and tissue remodeling. The expression of KLKs is detected in a broad spectrum of human tissues where it has been found to be regulated mainly by steroids hormones. The...

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PMID: 20302518
DOI: 10.1515/bc.2010.056

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