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Article

Genes inducing iPS phenotype play a role in hepatocyte survival and proliferation in vitro and liver regeneration in vivo.

Hepatology (Baltimore, Md.) - 1 Oct 2011

Bhave Vishakha S, Paranjpe Shirish, Bowen William C, Donthamsetty Shashikiran, Bell Aaron W, Khillan Jaspal S, Michalopoulos George K

Abstract excerpt

UNLABELLED: Reprogramming factors have been used to induce pluripotent stem cells as an alternative to somatic cell nuclear transfer technology in studies targeting disease models and regenerative medicine. The neuronal repressor RE-1 silencing transcription factor (REST) maintains self-renewal and pluripotency in mouse embryonic stem cells by maintaining the expression of Oct3/4, Nanog, and cMyc. We report that...

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Source

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Identifiers

PMID: 21739467
DOI: 10.1002/hep.24507
PMCID: PMC3184195

Genes

REST
EGF
HGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genes inducing iPS phenotype play a role in hepatocyte survival and proliferation in vitro and liver regeneration in vivo.PMID 21739467Read ↗

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Canonical Wnt/β-Catenin Regulation of Liver Receptor Homolog-1 Mediates Pluripotency Gene ExpressionSemantic proximity Read ↗

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