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Article

Molecular modelling of the emergence of azole resistance in Mycosphaerella graminicola.

PloS one - 1 Jan 2011

Mullins Jonathan G L, Parker Josie E, Cools Hans J, Togawa Roberto C, Lucas John A, Fraaije Bart A, Kelly Diane E, Kelly Steven L

Abstract excerpt

A structural rationale for recent emergence of azole (imidazole and triazole) resistance associated with CYP51 mutations in the wheat pathogen Mycosphaerella graminicola is presented, attained by homology modelling of the wild type protein and 13 variant proteins. The novel molecular models of M. graminicola CYP51 are based on multiple homologues, individually identified for each variant, rather than using a...

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Source

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Identifiers

PMID: 21738598
DOI: 10.1371/journal.pone.0020973
PMCID: PMC3124474

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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