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Article

From SNPs to genes: disease association at the gene level.

PloS one - 1 Jan 2011

Lehne Benjamin, Lewis Cathryn M, Schlitt Thomas

Abstract excerpt

Interpreting Genome-Wide Association Studies (GWAS) at a gene level is an important step towards understanding the molecular processes that lead to disease. In order to incorporate prior biological knowledge such as pathways and protein interactions in the analysis of GWAS data it is necessary to derive one measure of association for each gene. We compare three different methods to obtain gene-wide test...

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Identifiers

PMID: 21738570
DOI: 10.1371/journal.pone.0020133
PMCID: PMC3128073

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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