Article
Identification of the AFD neuron as the site of action of the CREB protein in Caenorhabditis elegans thermotaxis.
EMBO reports - 8 Jul 2011
Nishida Yukuo, Sugi Takuma, Nonomura Mayu, Mori Ikue
Abstract excerpt
Behaviour is a consequence of computation in neural circuits composed of massive synaptic connections among sensory neurons and interneurons. The cyclic AMP response element-binding protein (CREB) responsible for learning and memory is expressed in almost all neurons. Nevertheless, we find that the Caenorhabditis elegans CREB orthologue, CRH-1, is only required in the single bilateral thermosensory neuron AFD,...
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