Article
High-throughput optical quantification of mechanosensory habituation reveals neurons encoding memory in Caenorhabditis elegans.
Proceedings of the National Academy of Sciences of the United States of America - 2 Dec 2014
Sugi Takuma, Ohtani Yasuko, Kumiya Yuta, Igarashi Ryuji, Shirakawa Masahiro
Abstract excerpt
A major goal of neuroscience studies is to identify the neurons and molecules responsible for memory. Mechanosensory habituation in Caenorhabditis elegans is a simple form of learning and memory, in which a circuit of several sensory neurons and interneurons governs behavior. However, despite the usefulness of this paradigm, there are hardly any systems for rapid and accurate behavioral genetic analysis. Here, we...
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