Article
Ca2+ signaling via the neuronal calcium sensor-1 regulates associative learning and memory in C. elegans.
Neuron - 1 Apr 2001
Gomez M, De Castro E, Guarin E, Sasakura H, Kuhara A, Mori I, Bartfai T, Bargmann C I, Nef P
Abstract excerpt
On a radial temperature gradient, C. elegans worms migrate, after conditioning with food, toward their cultivation temperature and move along this isotherm. This experience-dependent behavior is called isothermal tracking (IT). Here we show that the neuron-specific calcium sensor-1 (NCS-1) is essential for optimal IT. ncs-1 knockout animals show major defects in IT behavior, although their chemotactic, locomotor,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.