Article
Tap withdrawal circuit interneurons require CREB for long-term habituation in Caenorhabditis elegans.
Behavioral neuroscience - 1 Aug 2011
Timbers Tiffany A, Rankin Catharine H
Abstract excerpt
We investigated the role of the Caenorhabditis elegans CREB (cAMP response element binding protein) homologue, crh-1, in response to tap (nonlocalized mechanosensory stimulation) and tap habituation. Worms with a loss-of-function mutation in crh-1 performed smaller reversals in response to tap than did wild-type worms and did not show long-term memory for spaced training 24-hr posttraining; however, they did show...
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