Article
[Phenotypic and histologic characteristics of cutaneous melanoma in patients with melanocortin-1 receptor polymorphisms].
Actas dermo-sifiliograficas - 1 Jan 2000
Avilés J A, Lázaro P, Fernández L P, Benítez J, Ibarrola-Villava M, Ribas G
Abstract excerpt
BACKGROUND: The melanocortin-1 receptor (MC1R) is an important risk factor for melanoma due to its role in the production of melanin in response to sun exposure. OBJECTIVES: To analyze the phenotypic and histologic characteristics of cutaneous melanoma in patients carrying mutations in MC1R and assess the influence of sun exposure on the occurrence of melanoma. MATERIAL AND METHODS: A total of 224 patients with a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
