Article
The histone variant H2A.Z interconverts two stable epigenetic chromatin states.
The Biochemical journal - 1 Nov 2011
Zhao Jin, Siew Wee Leng, Sun Weiqi, Lehming Norbert
Abstract excerpt
The nucleosomes occupying the chromosomal start sites of transcription contain the histone H2A variant H2A.Z in place of H2A. Upon galactose induction, nucleosomes are evicted from the GAL1 locus in Saccharomyces cerevisiae cells. H2A.Z (which is encoded by the HTZ1 gene in S. cerevisiae) is required for the eviction of the GAL1 promoter nucleosome and for the transcriptional activation of the GAL1 gene; however,...
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