Article
Phenotypic analysis of perennial airborne allergen-specific CD4+ T cells in atopic and non-atopic individuals.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Nov 2011
Crack L R, Chan H W, McPherson T, Ogg G S
Abstract excerpt
BACKGROUND: Accumulating evidence suggests that T cells play an important role in the pathogenesis of atopic dermatitis (AD); yet, little is known of the differentiation status of CD4+ T cells specific for common environmental allergens, such as the major cat allergen, Fel d 1. OBJECTIVE: To determine the frequency, differentiation phenotype and function of circulating Fel d 1-specific CD4+ T cells in adult...
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