Definition of a pool of epitopes that recapitulates the T cell reactivity against major house dust mite allergens

doi:10.1111/cea.12507

Article

Definition of a pool of epitopes that recapitulates the T cell reactivity against major house dust mite allergens

5 Feb 2015

Abstract excerpt

BACKGROUND: Allergens from house dust mites (HDM) are a common cause of asthma. Der p and Der f from Dermatophagoides sp. are strong immunogens in humans. Allergen extracts are used to study T helper (Th2) cell responses to HDM, which are implicated in the development and regulation of allergic disease. OBJECTIVE: To define an epitope mixture that recapitulates, and might substitute for, HDM extract in terms of...

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