Article
Temporal dynamic changes of phenotypic expression of peripheral CD4 cells during environmental allergen challenge in an experimental model of canine atopic dermatitis: a pilot study.
The Journal of veterinary medical science - 1 Sept 2009
Simpson Andrew, Maeda Sadatoshi, Marsella Rosanna
Abstract excerpt
The immunopathology behind atopic dermatitis (AD) involves a myriad of inflammatory cells and their mediators. Thymus and activation-regulated chemokine (TARC) plays a significant role in the inflammatory phase by recruiting CCR4(+) T(H)2 cells. In addition, CD25(+) activated T cells further propagate the allergic response after sensitization by producing cytokines. The purpose of this pilot study was to evaluate...
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