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Article

CR1 genotype is associated with entorhinal cortex volume in young healthy adults.

Neurobiology of aging - 1 Nov 2011

Bralten Janita, Franke Barbara, Arias-Vásquez Alejandro, Heister Angelien, Brunner Han G, Fernández Guillén, Rijpkema Mark

Abstract excerpt

Gene-brain structure associations of 3 recently discovered risk genes for Alzheimer's disease, CLU (rs11136000C>T), CR1 (rs6656401G>A), and PICALM (rs3851179G>A), were investigated in 2 independent cohorts of young healthy adults (n = 430 and n = 492, respectively). We assessed structural differences in 2 core structures of Alzheimer pathology, entorhinal cortex and hippocampus, by voxel-based morphometry using...

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Source

Identifiers

PMID: 21726919
DOI: 10.1016/j.neurobiolaging.2011.05.017

Genes

CLU
PICALM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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