Article
Lack of association between CD58 genetic variations and aspirin-exacerbated respiratory disease in a Korean population.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Aug 2011
Pasaje Charisse Flerida A, Bae Joon Seol, Park Byung-Lae, Cheong Hyun Sub, Jang An-Soo, Uh Soo-Taek, Kim Mi-Kyeong, Kim Jeong-Hyun, Park Tae-Joon, Lee Jin-Sol, Kim Yongha, Park Choon-Sik, Shin Hyoung Doo
Abstract excerpt
BACKGROUND: Exacerbation of asthma symptoms due to aspirin ingestion may lead to life-threatening lung failure. The adhesion molecule CD58 gene may play a crucial role in aspirin-exacerbated respiratory disease (AERD) pathogenesis by mediating the biological functions of asthma-inducing mechanisms including T helper cells, proinflammatory cytokines, and natural killer T cells. OBJECTIVE: This study aimed to...
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