Article
A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese.
Nature genetics - 3 Jul 2011
Hu Zhibin, Wu Chen, Shi Yongyong, Guo Huan, Zhao Xueying, Yin Zhihua, Yang Lei, Dai Juncheng, Hu Lingmin, Tan Wen, Li Zhiqiang, Deng Qifei, Wang Jiucun, Wu Wei, Jin Guangfu, Jiang Yue, Yu Dianke, Zhou Guoquan, Chen Hongyan, Guan Peng, Chen Yijiang, Shu Yongqian, Xu Lin, Liu Xiangyang, Liu Li, Xu Ping, Han Baohui, Bai Chunxue, Zhao Yuxia, Zhang Haibo, Yan Ying, Ma Hongxia, Chen Jiaping, Chu Mingjie, Lu Feng, Zhang Zhengdong, Chen Feng, Wang Xinru, Jin Li, Lu Jiachun, Zhou Baosen, Lu Daru, Wu Tangchun, Lin Dongxin, Shen Hongbing
Abstract excerpt
Lung cancer is the leading cause of cancer-related deaths worldwide. To identify genetic factors that modify the risk of lung cancer in individuals of Chinese ancestry, we performed a genome-wide association scan in 5,408 subjects (2,331 individuals with lung cancer (cases) and 3,077 controls) followed by a two-stage validation among 12,722 subjects (6,313 cases and 6,409 controls). The combined analyses...
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