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Metabolic Pathways Required for the Intracellular Survival of Leishmania

27 Sept 2010

Abstract excerpt

Leishmania spp. are sandfly-transmitted parasitic protozoa that cause a spectrum of important diseases and lifelong chronic infections in humans. In the mammalian host, these parasites proliferate within acidified vacuoles in several phagocytic host cells, including macrophages, dendritic cells, and neutrophils. In this review, we discuss recent progress that has been made in defining the nutrient composition of...

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PMID: 21721937
DOI: 10.1146/annurev-micro-090110-102913

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