Article
The transcription factor repertoire of Flt3+ hematopoietic stem cells.
Cells, tissues, organs - 1 Jan 2008
Hieronymus Thomas, Ruau David, Ober-Blöbaum Julia, Baek Jea-Hyun, Rolletschek Alexandra, Rose-John Stefan, Wobus Anna M, Müller Albrecht M, Zenke Martin
Abstract excerpt
Hematopoietic stem cells maintain the development of all mature blood cells throughout life due to their sustained self-renewal capacity and multilineage differentiation potential. During development into specific cell lineages, the options of stem cells and multipotent progenitor cells become increasingly restricted concomitant with a successive decline in self-renewal potential. Here we describe an Flt3+CD11b+...
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