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Article

Cancer stem cell overexpression of nicotinamide N-methyltransferase enhances cellular radiation resistance.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Jun 2011

D'Andrea Filippo P, Safwat Akmal, Kassem Moustapha, Gautier Laurant, Overgaard Jens, Horsman Michael R

Abstract excerpt

BACKGROUND: Cancer stem cells are thought to be a radioresistant population and may be the seeds for recurrence after radiotherapy. Using tumorigenic clones of retroviral immortalized human mesenchymal stem cell with small differences in their phenotype, we investigated possible genetic expression that could explain cancer stem cell radiation resistance. METHODS: Tumorigenic mesenchymal cancer stem cell clones...

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Source

Identifiers

PMID: 21719135
DOI: 10.1016/j.radonc.2011.05.086

Genes

NNMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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