Article
Mouse models of medulloblastoma.
Chinese journal of cancer - 1 Jul 2011
Wu Xiaochong, Northcott Paul A, Croul Sidney, Taylor Michael D
Abstract excerpt
Medulloblastoma is the most common malignant pediatric brain tumor. Despite its prevalence and importance in pediatric neuro-oncology, the genes and pathways responsible for its initiation, maintenance, and progression remain poorly understood. Genetically engineered mouse models are an essential tool for uncovering the molecular and cellular basis of human diseases, including cancer, and serve a valuable role as...
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