Article
[Genotypic survey of Plasmodium falciparum based on the msp1, msp2 and glurp genes by multiplex PCR].
Biomedica : revista del Instituto Nacional de Salud - 1 Jan 2000
Barrera Sandra Milena, Pérez Manuel Alberto, Knudson Angélica, Nicholls Rubén Santiago, Guerra Angela Patricia
Abstract excerpt
INTRODUCTION: The genetic diversity of Plasmodium falciparum has been one of the major obstacles for the success of anti-malaria drug therapy. It provides the parasite an ability to evade the host's immune response by generating changes in its antigenic composition and resistance to antimalarial drugs. OBJECTIVE: The genetic diversity of P.falciparum was characterized in 4 Colombian localities through the...
Topics
- Animals
- Antigens, Protozoan
- Genetic Variation
- Genotype
- Humans
- Malaria, Falciparum
- Merozoite Surface Protein 1
- Plasmodium falciparum
- Polymerase Chain Reaction
- Polymorphism, Genetic
