Genetic diversity of glutamate-rich protein (GLURP) in Plasmodium falciparum isolates from school-age children in Kinshasa, DRC.

doi:10.1016/j.parint.2024.102866

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Article

Genetic diversity of glutamate-rich protein (GLURP) in Plasmodium falciparum isolates from school-age children in Kinshasa, DRC.

Parasitology international - 1 Jun 2024

Paul Kambale Mathe Mowa, Simpson Shirley V, Nundu Sabin S, Arima Hiroaki, Yamamoto Taro

Abstract excerpt

Malaria infections in school-age children further make it difficult to control the disease's spread. Moreover, the genetic diversity of glutamate-rich protein, potentially a candidate for vaccine development, has not yet been investigated in the Democratic Republic of Congo. Therefore, we aimed to assess the genetic diversity of the immunodominant C-terminal repetitive region (R2) of Plasmodium falciparum...

Topics

Child
Humans
Plasmodium falciparum
Malaria, Falciparum
Glutamic Acid
Democratic Republic of the Congo
Protozoan Proteins
Mutation
Genetic Variation

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Open in PubMed

Identifiers

PMID: 38350548
DOI: 10.1016/j.parint.2024.102866

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