Article
Genetic Characterisation of Plasmodium falciparum Isolates with Deletion of the pfhrp2 and/or pfhrp3 Genes in Colombia: The Amazon Region, a Challenge for Malaria Diagnosis and Control.
PloS one - 1 Jan 2016
Dorado Erika Jimena, Okoth Sheila Akinyi, Montenegro Lidia Madeline, Diaz Gustavo, Barnwell John W, Udhayakumar Venkatachalam, Murillo Solano Claribel
Abstract excerpt
Most Plasmodium falciparum-detecting rapid diagnostic tests (RDTs) target histidine-rich protein 2 (PfHRP2). However, P. falciparum isolates with deletion of the pfhrp2 gene and its homolog gene, pfhrp3, have been detected. We carried out an extensive investigation on 365 P. falciparum dried blood samples collected from seven P. falciparum endemic sites in Colombia between 2003 and 2012 to genetically...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.