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Article

Genetic polymorphisms in the glutamate-rich protein of Plasmodium falciparum field isolates from a malaria-endemic area of Brazil.

Memorias do Instituto Oswaldo Cruz - 1 Jun 2013

Pratt-Riccio Lilian Rose, Perce-da-Silva Daiana de Souza, Lima-Junior Josué da Costa, Theisen Michael, Santos Fátima, Daniel-Ribeiro Cláudio Tadeu, de Oliveira-Ferreira Joseli, Banic Dalma Maria

Abstract excerpt

The genetic diversity displayed by Plasmodium falciparum, the most deadly Plasmodium species, is a significant obstacle for effective malaria vaccine development. In this study, we identified genetic polymorphisms in P. falciparum glutamate-rich protein (GLURP), which is currently being tested in clinical trials as a malaria vaccine candidate, from isolates found circulating in the Brazilian Amazon at variable...

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Identifiers

PMID: 23828006
DOI: 10.1590/S0074-02762013000400022
PMCID: PMC3970628

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Source receipt: pubmed, retrieved 7 Sept 2026.

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