Article
Prevalence of obesity was related to HLA-DQ in 2-4-year-old children at genetic risk for type 1 diabetes.
International journal of obesity (2005) - 1 Dec 2014
Yang J, Lernmark Å, Uusitalo U M, Lynch K F, Veijola R, Winkler C, Larsson H E, Rewers M, She J-X, Ziegler A G, Simell O G, Hagopian W A, Akolkar B, Krischer J P, Vehik K
Abstract excerpt
OBJECTIVES: Body size is postulated to modulate type 1 diabetes as either a trigger of islet autoimmunity or an accelerator to clinical onset after seroconversion. As overweight and obesity continue to rise among children, the aim of this study was to determine whether human leukocyte antigen DQ (HLA-DQ) genotypes may be related to body size among children genetically at risk for type 1 diabetes. METHODS:...
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