Article
Selective inner retinal dysfunction in growth hormone transgenic mice.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society - 1 Aug 2011
Martin Brent T, List Edward O, Kopchick John J, Sauvé Yves, Harvey Steve
Abstract excerpt
OBJECTIVE: The discovery of locally produced growth hormone (GH) and its receptor in the retina of rodents raises the possibility that GH might modulate retinal function. To test this hypothesis, we determined the retinal electroretinogram (ERG) of bovine GH (bGH) transgenic mice. DESIGN: ERGs were recorded from 11 wild type (WT) and 9 bGH mice, at 2 months of age in response to a series of light flashes at...
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