Article
Uncovering amyotrophic lateral sclerosis phenotypes: clinical features and long-term follow-up of upper motor neuron-dominant ALS.
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases - 1 Jul 2011
Sabatelli Mario, Zollino Marcella, Luigetti Marco, Grande Alessandra Del, Lattante Serena, Marangi Giuseppe, Monaco Mauro Lo, Madia Francesca, Meleo Emiliana, Bisogni Giulia, Conte Amelia
Abstract excerpt
The aim of our study was to analyse the natural history and clinical features of upper motor neuron- dominant (UMN-D) ALS. We studied a large series of sporadic ALS patients admitted in a single referral centre over a 23-year period. UMN-D phenotype was compared with other ALS forms, including classic ALS, flail arm and progressive muscular atrophy. Seven hundred and thirty-four sporadic ALS patients were...
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