Article
The secD locus of E.coli codes for two membrane proteins required for protein export.
The EMBO journal - 1 Oct 1990
Gardel C, Johnson K, Jacq A, Beckwith J
Abstract excerpt
Cold-sensitive mutations in the secD locus of Escherichia coli result in severe defects in protein export at the non-permissive temperature of 23 degrees C. DNA sequence of a cloned fragment that includes the secD locus reveals open reading frames for seven polypeptide chains. Both deletions and...
Topics
- Amino Acid Sequence
- Bacterial Proteins
- Base Sequence
- Chromosome Deletion
- Chromosomes, Bacterial
- Cloning, Molecular
- Cold Temperature
- DNA Transposable Elements
- Escherichia coli
- Genetic Complementation Test
- Membrane Proteins
- Molecular Sequence Data
- Mutation
- Operon
- Plasmids
- Protein Conformation
- Restriction Mapping
- Sequence Homology, Nucleic Acid