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Early detection of Alzheimer disease

24 Jun 2011

Abstract excerpt

OBJECTIVE: The aim of this study was to investigate whether cognitively preserved monozygotic or dizygotic cotwins of persons with Alzheimer disease (AD) exhibit increased brain amyloid accumulation. METHODS: We performed a cross-sectional carbon-11 labeled 2-(4'-methylaminophenyl)-6-hydroxybenzothiazole ((11)C)-Pittsburgh compound B (PiB) PET study on 9 monozygotic and 8 dizygotic twin pairs discordant for...

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PMID: 21700581
DOI: 10.1212/wnl.0b013e318225118e

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