Article
Novel SNPs of the mannan-binding lectin 2 gene and their association with production traits in Chinese Holsteins.
Genetics and molecular research : GMR - 15 Oct 2012
Zhao Z L, Wang C F, Li Q L, Ju Z H, Huang J M, Li J B, Zhong J F, Zhang J B
Abstract excerpt
The mannan-binding lectin gene (MBL) participates as an opsonin in the innate immune system of mammals, and single nucleotide polymorphisms (SNPs) in MBL cause various immune dysfunctions. In this study, we detected SNPs in MBL2 at exon 1 using polymerase chain reaction single-strand conformation polymorphism analysis and DNA sequencing techniques in 825 Chinese Holstein cows. Four new SNPs with various...
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