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Article

Induction and maintenance of the neuronal cholinergic phenotype in the central nervous system by BMP-9.

Science (New York, N.Y.) - 14 Jul 2000

López-Coviella I, Berse B, Krauss R, Thies R S, Blusztajn J K

Abstract excerpt

Bone morphogenetic proteins (BMPs) have multiple functions in the developing nervous system. A member of this family, BMP-9, was found to be highly expressed in the embryonic mouse septum and spinal cord, indicating a possible role in regulating the cholinergic phenotype. In cultured neurons, BMP-9 directly induced the expression of the cholinergic gene locus encoding choline acetyltransferase and the vesicular...

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Share to Acetylcholine
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Source

Identifiers

PMID: 10894782
DOI: 10.1126/science.289.5477.313

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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