Article
Cholinergic expression by a neural stem cell line grafted to the adult medial septum/diagonal band complex.
Journal of neuroscience research - 15 Sept 2000
Doering L C, Snyder E Y
Abstract excerpt
The potential of a neural stem cell line to acquire cholinergic characteristics was studied in transplants injected into the septum/diagonal band nuclei of young adult rats and mice. The stem cells integrated within the nuclei and survived for up to 9 months. Three methods were used to identify the grafted cells and to show differentiation into astrocytes and neurons. Enhanced survival of the stem cells occurred...
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