Article
Impaired cardiac sympathetic innervation in symptomatic patients with long QT syndrome.
European journal of nuclear medicine and molecular imaging - 1 Oct 2011
Kies Peter, Paul Matthias, Gerss Joachim, Stegger Lars, Mönnig Gerold, Schober Otmar, Wichter Thomas, Schäfers Michael, Schulze-Bahr Eric
Abstract excerpt
PURPOSE: Increased sympathetic activation is a key modifier for arrhythmogenesis in patients with long QT syndrome (LQTS), a congenital channelopathy. Therefore, we investigated cardiac sympathetic function using 123I-metaiodobenzylguanidine (MIBG) single photon emission computed tomography (SPECT) in a cohort of symptomatic LQTS patients and correlated these findings with the underlying genotype. METHODS:...
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