Article
Cardiac sympathetic dysfunction in genotyped patients with arrhythmogenic right ventricular cardiomyopathy and risk of recurrent ventricular tachyarrhythmias.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine - 1 Oct 2011
Paul Matthias, Wichter Thomas, Kies Peter, Gerss Joachim, Wollmann Christian, Rahbar Kambiz, Eckardt Lars, Breithardt Günter, Schober Otmar, Schulze-Bahr Eric, Schäfers Michael
Abstract excerpt
UNLABELLED: Patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) typically present with ventricular tachyarrhythmias preferentially triggered by an elevated sympathetic tone. Previous studies demonstrated an impairment of the presynaptic catecholamine reuptake as assessed by (123)I-labeled norepinephrine analog on metaiodobenzylguanidine ((123)I-MIBG) SPECT. Mutations in the gene encoding for...
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